GEOMETRICAL ISOMERISM IN β-NITROSTYRENES: PREFERRED CONFORMATIONS OF (E)- AND (Z)- 1-(4-METHYLTHIOPHENYL)-2-NITROBUTENES
نویسندگان
چکیده
منابع مشابه
Conformational isomerism of phenolic procyanidins: preferred conformations in organic solvents and water
NMR studies of catechin-{40-.+8)-epicatechin (I) and catechin-{40-.+8)-catechin (2) provided complete assignment of the proton and carbon resonances for both the more extended and compact conformers in the free phenolic form. When I is in organic solvents, the more extended rotamer is preferred over the more compact rotamer (10:7), but in water, the compact rotamer dominates (2: 10). When 2 is ...
متن کاملInvestigation of Z-E Isomerism in Sunitinib Anticancer drug
Accepted on 8 th April 2014 _____________________________________________________________________________ ABSTRACT Z-E isomerization in sunitinib, an important anticancer drug, has been investigated. The influence of light, heat and solvent was studied and the isomerizations were monitored by HPLC. As expected, the extent of Z-E isomerization (conversion of the Z-isomer into the undesired E-iso...
متن کاملCrystal structure of methyl (Z)-2-[(Z)-3-methyl-2-({(E)-1-[(R*)-4-methylcyclohex-3-en-1-yl]ethylidene}hydrazinylidene)-4-oxothiazolidin-5-ylidene]acetate
The new title 4-thia-zolidinone derivative, C16H21N3O3S, was obtained from the cyclization reaction of 4-methyl-3-thio-semicarbazone and dimethyl acetyl-enedi-carboxyl-ate (DMAD). The cyclo-hexyl-idene ring has an envelope conformation with the stereogenic centre C atom as the flap. Its mean plane makes a dihedral angle of 56.23 (9)° with the thia-zolidine ring mean plane. In the crystal, mol-e...
متن کاملE-[4-(β-d-Allopyranosyloxy)phenyl]-1-(4-chlorophenyl)prop-2-enone ethanol solvate
The title compound, C(21)H(21)ClO(7)·C(2)H(5)OH was synthesized by the condensation reaction between helicid [systematic name: 4-(β-d-allopyranos-yloxy)benzaldehyde] and 4-chloro-aceto-phen-one in ethanol. In the mol-ecular structure, the pyran-oside ring adopts a chair conformation. In the crystal structure, the molecules are linked by inter-molecular O-H⋯O hydrogen bonds involving the OH grou...
متن کاملβ-Nitrostyrenes as Potential Anti-leishmanial Agents
Development of new therapeutic approach to treat leishmaniasis has become a priority. In the present study, the antileishmanial effect of β-nitrostyrenes was investigated against in vitro promastigotes and amastigotes. A series of β-nitrostyrenes have been synthesized by using Henry reaction and were evaluated for their antimicrobial activities by broth microdilution assay and in vitro antileis...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the Chilean Chemical Society
سال: 2004
ISSN: 0717-9707
DOI: 10.4067/s0717-97072004000300013